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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49f21b9f4676d8d54068d525ddf2f0da45f8cbc07f1a864ac73d7eb70df1e52d' 
  AND token = 'RwthKaZTP3o8kZFhH3ApuECihXZhPU3MDtR7seUulUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}