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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84b9883076c2cfc8d993fc13eacf47998aeb701312e66af83d04483c5472cf00' 
  AND token = 'mubXSjvweBZ8x+I3xt6yAIZgwSbZ5Q4UbEhZ4ddGmo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}