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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed7c66e2494ab4bb5005d898b7f36905b564c3d3cd343c663880775774b9b3e1' 
  AND token = 'L+pPzWoJJ0gHlsPgC42qEzVAriMcA9kCUmWGJVnUDmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}