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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64722160a1f96c49db5b2ddf77b10c15eafaa3c4a92b56323133a3c07fa81e5c' 
  AND token = 'JZZt6LSjbUcsqbdhVMrGBmDCiC61A3JFAU9BBG1VFz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}