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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0aad5c31bc1503d072a745519cf36e2c64fde8f2a191b9cb2c06d9f438ab1d3' 
  AND token = 'OMqqHOI1FYunLnYlAhA7L9eys1nNXt1/y7F0z+F00GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}