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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e24e9b8fd4d354ab08952b1cf68bb4e205d481e1c2317b1e8cb83b1d6803f7a5' 
  AND token = '+q5rHoCUPIPB4S1vHrwBBLVa2M9eyaVnWMX5y+uk5cI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}