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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2000cb7159fa69bb796c7e7d34d00420786a71b4f846c64e4cb6959f84787f80' 
  AND token = 'jkm0sYQoGtbC5+TCRlkQHEyAJCjyjeVKWp1NR7o7ZSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}