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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1cd72e0925432f2f72467a39a9c23aa2575fa3ff86b76634240188ef288493a' 
  AND token = '9i/rKSkPDMZV8vQby6EPLDmDnOwWuMXkA2zfh3IPhqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}