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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a43c051d008bef9088248b701517cce551e6ab0a003223fffbf700e781ee904b' 
  AND token = 'JFJgRxkmnrEVQK6XTCQ5JEAFgMgRtaf5E0aYlPzDQTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}