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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46e12f804a5043dc07f17ca35fe979896d480649eb1e06265cc2ce3898cde50f' 
  AND token = 'txm3QFI7lMjJT5LcTgHUs55cwcEW8Edf2NYmOyd3ej4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}