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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a74b27abb06b64e18da0b0d42bb5af5fa5f95b4e1a46203fa8f935038d3cf395' 
  AND token = '1c4MyENCpe96CdgaOMKFMump8G9fz7rNGtlkPdAAjck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}