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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '684faf3c23eb947e1afb40f1418221230d408c3f48946826874dc02df9b801ca' 
  AND token = '1ytEuu3OHZ060YiRc30IOMRWkBEBkK/3DOEp5xIE9c8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}