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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c4a3c01e6f5607eff6a3ed6b0d3f1d920b89b8db4149d502323354cfcb115e8' 
  AND token = 'DtvBoeStCZSW2gm7PZ8k0DBuCy8sDT5M3zqOCETCNXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}