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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10fa69acd214f2e94b441304a1060ae0f39dbe62b68e28d27c4816649ea7f8b4' 
  AND token = '1SS7RNvn1+xuB4SHSwIuFmRsWfraGzA7fxqLtyAVhO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}