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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7875d3443e2430b59e330df833ae1f439c04def0049fb21b44e58873e9e8a3d4' 
  AND token = 'cuay1clUBPoj/mg6zbY8vVWCrggrkY+LF4HsKNDOVzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}