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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65d3071c7e977bbb5d8dcd81ffbff165d147a71778053eb3c5d0d194d4d651a7' 
  AND token = 'Mye9/hMx8xW3+2Mf3p6zvcVPaelAhz0SziaAv8oM7rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}