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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '791b903f0c08d3b9241f5491afd018ef0251e28925942cee65106084eb5b762b' 
  AND token = 'cXq8XR6vW0dIc+z9lbsuSiUYIay2FKypdvRG7sXEa4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}