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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95c420538f755631b15557795f4b0d60caaea643e7f8cdf2e29f42227a4b733e' 
  AND token = 'Uv4edmdXIl+iVyGpVfI0txnqh36fU0R6chrMH6vJq6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}