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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3271b8ff50bf2e1c9fec43e01c7b877f77f528b609b8a6c460a483bfd7abc3a8' 
  AND token = '+LJNelDU1pkunUFvmkqJAARWtG/O1b00WrlrLBc+kkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}