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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede068735882bd48892b0be2081d1015e8a5dc8b308616217c425a3e0dc53717' 
  AND token = 'AJbgzbZ/e4S9pR4hal538NtXT3b+DvsawQdcrP+GjEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}