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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57ef4e89c801a741f32520f1eb1037d851efd2c591d678796b58fc161fa756fd' 
  AND token = '7BPVkamMLgqhV66CXVL/9tuQVakhg8rYJDPPqsyfqE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}