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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc7e2dbe9d75e3d96fb429969a3f569c4d8e228da84bb43be99b7b4d31be9c0b' 
  AND token = 'ASL/AUge3RgDYkOzFMXC2bWLvyFLuQDxMS7NDO9UR6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}