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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eab9c4e1c49b5350f5aa9aa18ff7ae0b1759f06a8f410fe784d4218f3fc72504' 
  AND token = '9ClRzrRUje6OYfyMIdUnSHf5qdxMvt2Pr+po5MRyOMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}