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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afc5444dcda911269d0ddec9b6dbe50a798e283f2da1b1b280be787efd6d5e35' 
  AND token = 'xdT6EMEqtMyPa8MDbExW9k+W5hxM1U3YFQj1UqkMBWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}