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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca1d3a3df7141741d81dadef7883232b08979f454e88c035c4b57a002a13e6b9' 
  AND token = 'DdkfeCStMdRHD2EQOPciSbP5E3lw6QTCxf+8dCPYNkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}