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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54fc5dabbd6c775bda4938faee7bf78c80bf69151dad5c17736fa0e2a097cc16' 
  AND token = 'kuH+/DH32mde72qQ8mQVSAPbGkkSbNf0qNIkUb/PRtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}