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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1160fba55999ba1a86b88c520e2c44189a453901bc413135600ed730a6cd357' 
  AND token = 'TZioniM0aD5QDlVfWxd2BeJjOdoWUdI390EsVCeuz+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}