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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c163d5ba069b8fe118ff3fb65b7f0dfe17ae68611b790156bf89d9492d01e6fe' 
  AND token = 'W8eCwYFpCC9yih5E+ZmMZ3ndNSvMmxvFZQnNV6D6Xps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}