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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b8a738af1dc5b51ed7091b39ba5c880b1301bbdd5b5db6425cae5375678c8ab' 
  AND token = 'RKZ4l2lcSZSG+tEAM/0GMbYphiQZy8hwjleZt4Clkfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}