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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aea2b62ee1891922a2bb75f8e1e8c585005f7d8ca63e964d37d2c5f07276f11' 
  AND token = 'Qzj5/2RPQro2orr0q98H2gwo39NWxztpxdPXwW9Bp9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}