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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b2ef26f396ad2875316897f0f1bbb81a630bb881c6d17bff650a421073bb4bc' 
  AND token = 'HI/oT/FjL6EId+qWk7XvdvpmyFY/EUww2Q+IOyk79EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}