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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95a8ec038f3e9c46621252d659051d9485e611f186204a68384ecc21ade9204a' 
  AND token = 'wvF4FM4GR/GGtWYkYYmHmtap2xzeGoR7XFQr7SrHldE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}