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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '166c40dcf7346d335689c55fa1630fca4b1d1aa58a1893a3359be2b5b3007b20' 
  AND token = '0THpMINLITUCSWFP7r+cXWB545XjKIEy9dkx54Nl1J4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}