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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fd9360e20ba6cf6f98ff4a66553a4d99e3dce1ad585b46504b8347a4f486888' 
  AND token = 'tJ9+gwluZ+i2GXNC5KTb5Fm+40pTYnu989DDj5sMojc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}