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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58e29ade67f77cc6eda3ebf6152737c57d6157c598423f06f79136bbc4f516be' 
  AND token = 'H229tHw01l36wC9zvIGtGEmREspMdux9JjUqYWXAiTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}