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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2956ae35adf08329ec3ce98a500943786f57fa683d66e50d1e118626f401029' 
  AND token = '2Ez5Q7jBlSNPO+rkuUlQYIsHhGSL+WST5Xt6Kzt2bKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}