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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '413a4e344bcf440ab26daf0646709051d81f5827bc47767c5c7da729518cebad' 
  AND token = 'b3XtCkExH/WWhKb4aNo0SKsTDoINFV7BrU1jPuFSI14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}