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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '642a432265b4202aebc94aa4c78afb853ccab712920aed8d7f1b879575ab0f95' 
  AND token = 'nc0+DGXQ5NFcNYk1LKpwaFMPVLH3khZw3KQffm+C1nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}