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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '438434c941485690b5ff7fbe8eb4c16f9e1e2b667f2f0b9b009b0ca60a24eef6' 
  AND token = 'MqID0m+r/yWDc7Blf6C2VyXeIKc9m/VMjFi0+E1L6Wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}