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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049763ca60ca44b295f8c84897675df509f1eb7f31a3800228d7fff840e86481' 
  AND token = '+0n+6FfDAG5GXK50tsKq9SPUzT4TS/fna7hVJFr/f78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}