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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca16905fd8685ff3cd786e8d355b87210f75748e398b83a0ee70fa2e726d2809' 
  AND token = 'pJ31+D3lZQXv9KUgk+7zDKQYpLlICb47EPaLy0ratmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}