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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f2ecde163db6d1b55c57129580182461505b11f9bd27ecf40fb9b1f2c1576e' 
  AND token = 'RSjPSsv+iNwjQhGcoyIbh+7E9zE09VLn52mndvAqAo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}