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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f30c17403f036d41cd4d2cd2b264be0bd8bf0dca9c096940ac9375c0515830' 
  AND token = '9Kfi1ogspMICWiYHqRKSUHuNx0FLSZ8rJ+JK8JrNDPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}