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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92bb9995423d80645a9a396620a3578d261644869c5dc8ff2136d85c01ed8c9b' 
  AND token = 'PV4Z2ItVgdESnv8K0ziwhzYkZ88nLv3ZtQZf9es67DU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}