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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7612601945d42a478875e7500b727e96df84961605884b90e09edcf13038ffa' 
  AND token = '/dGM1gSHaC4oQEoDbHm9sOnX10LBUMs27SFjH1JA3Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}