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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d5a780dc070855f38ea6df2c835cf1c16c053c0ef1b6f31e86cd0ccbd28ae9' 
  AND token = 'ZZPfQtn4w//HF1FM2h25s8wkTfZEqWrgSQtc5Jz1SPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}