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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f356e578f8db5f9df61aaf86644a0423dc0c463301bfd705d99ab5939beb0f66' 
  AND token = '2Xj1BCW77nLDQPlHGKdEYoQx3I8+kBrBG7rGmS7j6gY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}