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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08e48c8674318543b8f4c4cac9173c3fd9a72219cab5152365aa2b6c6954f768' 
  AND token = 'sHDeCqrJMzJ1hHmbj3FyMSdY0LW3pim3MnIZ2xFYI3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}