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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7cfccc2d7107931f8686e37488264674331e16f14a49b30dc6fd480316f7a2' 
  AND token = 'shIKie5eTWq/x+Ew/zq3zo6TEjGr+joZ30eWecSgw/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}