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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bb8ab2c53119b8ffa08b6cfb34c73e975da1a3b78075b572083d7117df640d2' 
  AND token = 'qFcTuIzBo+Jcnsh5B7oh6dWDe0rJ9F2MvnqEgFeg4rI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}